Table 1 Characteristics of the included studies.
Study | Sample size | Age | Male rate (%) | Country | Study design | Intervention | Control | Outcomes |
|---|---|---|---|---|---|---|---|---|
Zhang et al.17 | 56 | 45.6 ± 11.9 | 42.8 | China | Randomized double-blinded controlled study | TXA (tranexamic acid) group (1 g diluted to 20 ml normal saline) | 20 ml normal saline | Bleeding score, Duration of surgery (minutes), Surgeon satisfaction |
Ziaei et al.18 | 73 | 33.0 | 55.1 | Iran | Randomized double-blinded controlled study | Tranexamic acid (10 mg/kg) | Normal saline with equal volume | Duration of surgery (minutes), amount of bleeding (ml), MAP (mmHg) |
Das et al.16 | 50 | 28.5 | 64.0 | India | Randomized double-blinded controlled study | Intravenous tranexamic acid bolus (10 mg/kg) half an hour | Normal saline with equal volume | Bleeding score, Duration of surgery (minutes), MAP (mmHg) |
Aghadavoudi et al.15 | 69 | 33.1 | 58.1 | Iran | Randomized double-blinded controlled study | Tranexamic acid (10 mg/kg) | No injection | Surgeon satisfaction, amount of bleeding (ml), MAP (mmHg) |
