Fig. 3

Mendelian randomization association of genetically predicted circulating proteins with ALS. Odds ratios are scaled per increase in standard-deviations of proteins. Detailed information for the proteins are provided in Supplemental Material. ALS, amyotrophic lateral sclerosis; CI, confidence interval; IVW, the inverse-variance weighted method; MR, Mendelian randomization; OR, odds ratio; SNP, single nucleotide polymorphism.