Fig. 1 | Scientific Reports

Fig. 1

From: Aquaporin 9 downregulation in KRASG12V colorectal cancer and associated with increased proliferation and decreased apoptosis in cancer cells

Fig. 1

Bioinformatics Analysis Identifies Aquaporin 9 (AQP9) as a Central Protein Linked to KRASG12V colorectal cancer (CRC). (A, B) Volcano plot showing differential gene expression between KRASG12V/KRASWT, KRASG12V/KRASOTHER in CRC. (C, D) Heat map of differentially expressed genes between KRASG12V/KRASWT, KRASG12V/KRASOTHER in CRC. (E) Venn diagram showing commonly differentially expressed genes in KRASG12V/KRASWT and KRASG12V/KRASOTHER of CRC. (F) Gene ontology analyses of commonly differentially expressed genes. (G) String protein-protein interaction analysis to identify AQP9. (H, I) AQP9 expression is significantly downregulated in CRC with KRASG12V compared to KRASWT and KRASOTHER.

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