Table 3 Correlation between ZHX2 expression and clinicopathological parameters of colorectal cancer.
Clinical and Pathological index | ZHX2 Expression | P | ||
|---|---|---|---|---|
Low | Medium | High | ||
Age | ||||
< 65 | 20 | 17 | 5 | 0.374 |
≥ 65 | 27 | 34 | 4 |  |
Gender | ||||
Male | 29 | 29 | 6 | 0.806 |
Female | 18 | 22 | 3 | Â |
Metastasis | ||||
Yes | 6 | 3 | 1 | 0.484 |
No | 38 | 45 | 7 | Â |
Node positive | ||||
Yes | 22 | 26 | 5 | 0.926 |
No | 18 | 20 | 3 | Â |
TNM | ||||
I-II | 18 | 23 | 6 | 0.427 |
III-IV | 24 | 26 | 3 | Â |
PD-L1 | ||||
Positive | 10 | 10 | 1 | 0.232 |
Negative | 4 | 8 | 1 | Â |
Macroscopic types | ||||
Ulcerative | 17 | 18 | 2 | 0.586 |
Infiltrative | 18 | 29 | 4 | Â |
Tumor location | ||||
Left-sided colon and rectum | 35 | 32 | 5 | 0.343 |
Right-sided colon | 12 | 19 | 4 | Â |
Tumor maximum diameter | ||||
≤ 4 (cm) | 12 | 44 | 4 | 0.001* |
> 4 (cm) | 35 | 7 | 5 |  |
MMR | ||||
Proficient | 45 | 49 | 8 | 0.631 |
Deficiency | 2 | 2 | 1 | Â |
Histological classification | ||||
Tubular adenocarcinoma | 40 | 33 | 6 | 0.751 |
Mucinous adenocarcinoma | 3 | 4 | 1 | Â |
Differentiation | ||||
Well | 6 | 3 | 2 | 0.134 |
Moderate | 32 | 29 | 7 | Â |
poor | 9 | 13 | 0 | Â |
KRAS | ||||
G12V | 9 | 2 | 0 | 0.004* |
WT | 27 | 23 | 3 | Â |
OTHER | 11 | 26 | 6 | Â |
AQP9 | 47 | 51 | 9 | Â |
Low | 18 | 6 | 1 | 0.016* |
Medium | 16 | 31 | 6 | Â |
High | 13 | 14 | 2 | Â |
