Fig. 1
From: Naringin attenuates angiotensin II induced cardiac hypertrophy by inhibiting carbonic anhydrase II
Molecular dynamics simulations of naringin with CA-II. (a) RMSD of naringin and CA-II complex, giving insight into its structural conformation throughout the simulation, showing fluctuation within the acceptable limit. (b) 2D geometrical interactive plot showing interactions of amino acids with naringin. (c) L-RMSF depicting the interaction of naringin atoms (given in percentage) with CA-II throughout the MDSs. (d) Summary of the interactions of CA-II-naringin complex in a normalized stacked bar chart. (e) The contact strengths between the putative binding site amino acids of CA-II with naringin throughout the MDS’s up to 200ns.
