Fig. 1
From: Differential association between cumulative dose of 5α-reductase inhibitors and mortality
Flowchart of the selection process of participants in the nested case-control study. (a) The Korea National Health Insurance Service-National Sample Cohort (NHIS-NSC) database is a longitudinal cohort comprising 1,024,340 participants, equivalent to 2.2% of the Korean population, spanning from January 1, 2002 to December 31, 2019. This database encompasses various sociodemographic variables, health insurance classifications, mortality records, medical checkup results, diagnostic information, and prescribed medications. (b) Participants who died following a diagnosis of benign prostatic hyperplasia or androgenic alopecia. (c) Age (± 1 year), sex (male or female), date of the first depression diagnosis (± 30 days), and follow-up duration. Abbreviations: BPH, benign prostate hyperplasia; AGA, androgenic alopecia, 5-ARI, 5-alpha reductase inhibitor.
