Table 2 The effect of 80% hydro-methanol extract of Solanum lycopersicum L. on urine volume in mice.

From: Diuretic activity of hydro-alcoholic extract and solvent fractions of Solanum lycopersicum L. leaves in mice

Groups

Volume of urine (ml)

Diuretic Action

Diuretic Activity

1 h

2 h

3 h

4 h

5 h

NC

0.43 ± 0.01

0.50 ± 0.01

0.59 ± 0.01

0.66 ± 0.01

0.72 ± 0.01

–

–

100 HME

0.46 ± 0.02

0.59 ± 0.01a2

0.74 ± 0.01a3

0.82 ± 0.02a3

0.86 ± 0.02a3

1.18

0.69

200 HME

0.61 ± 0.02(ab)3

0.66 ± 0.02a3b1

0.77 ± 0.01a3

0.89 ± 0.01a3

0.94 ± 0.01a3b1

1.30

0.76

400 HME

0.64 ± 0.01(ab)3

0.85 ± 0.01(abc)3

1.02 ± 0.04(abc)3

1.33 ± 0.03(abc)3

1.45 ± 0.03(abc)3

1.70

0.99

F 10

0.64 ± 0.01(ab)3

0.82 ± 0.02(abc)3

0.96 ± 0.01(abc)3

1.26 ± 0.06(abc)3

1.41 ± 0.02(abc)3

1.71

1.00

  1. Each value represents mean ± S.E.M; n = 6; a, against 2%TW80; b, against 100 mg HME; c, against 200 mg HME; d, against 400 mg HME; 1: p < 0.05, 2: p < 0.01, 3: p < 0.001; HME: 80% hydro methanol extract; F10: Furosemide 10 mg/kg; NC: Negative control, 100 HME: 100 mg hydro methanol extract, 200 HME: 200 mg hydro methanol extract, 400 HME: 400 mg hydro methanol extract.
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