Table 5 The correlation between the three Circulating DNA methylations and overall survival.

Yes (40)

35.0 ± 1.7

39.9 ± 2.4

35.9 ± 2.3

5.6 ± 1.0

No (22)

34.1 ± 2.8

37.0 ± 4.1

34.9 ± 2.8

6.4 ± 1.7

P value

–

**

–

–

Overall survival

 ≤ 6 months (4)

31.6 ± 0.8

31.1 ± 1.1

31.9 ± 1.5

8.4 ± 0.6

 > 6 months (58)

34.6 ± 2.8

38.4 ± 3.1

35.6 ± 2.6

5.9 ± 1.6

 P value

**

***

**

***

  ≤ 12 months (8)

33.3 ± 2.6

34.2 ± 4.3

33.6 ± 2.7

7.2 ± 1.8

> 12 months (54)

34.5 ± 2.9

38.7 ± 3.0

35.6 ± 2.8

5.9 ± 1.6

 P value

–

***

**

**

Median survival time

 ≤ 46.5 months (44)

34.8 ± 2.6

39.0 ± 3.9

35.6 ± 2.8

5.8 ± 1.6

 > 46.5 months (18)

34.3 ± 0.6

38.6 ± 1.7

35.3 ± 1.6

6.0 ± 0.5

 P value

–

–

–

–