Fig. 7
Observation of gastric injury after NETs inhibition. (a): Gastric injury in each group; (b): Pathology observation (× 400, scale bar = 50 µm, green arrow: shed epithelial cells, 
: lymphocyte, 
: degeneration and necrosis of mucosa; (c): Observation of ultrastructure of GECs under TEM (× 30,000, scale bar = 500 nm), N: nucleus, Mi: mitochondrion, RER: rough endoplasmic reticulum, MV: microvilli; 
: normal mitochondrion, 
: expanded rough endoplasmic reticulum, 
: mitochondrial swelling, 
: fading of the cell membranes, 
: permeabilization of mitochondrial outer membrane, 
: loss of ribosomes. (d): ROS contents in each group, bar: mean ± SE, n = 3; (e): MPO-DNA concentration in each group, bar: mean ± SE, n = 6; (f): H3Cit concentration in each group, bar: mean ± SE, n = 4; (g): TNF-α concentration in each group, bar: mean ± SE, n = 6; (h): IL-1β concentration in each group, bar: mean ± SE, n = 6; vs control group, **P < 0.01, *P < 0.05; vs model group, ##P < 0.01, #P < 0.05.
