Fig. 6
From: The DUF1669 domain of FAM83H is required for its localization to nuclear speckles
The FAM83H mutants used in the study. Full-length FAM83H comprises 1179 amino acid residues. The amino acid lengths of the FAM83H mutants used in this study are shown in light gray columns. Yellow columns indicate the DUF1669 domain. Dark-gray columns indicate the amino acid residues of the FLAG-tag (F). Red lines indicate the positions of keratin localization residues (K, 1134–1139). Green columns indicate GFP. The ○, △, and × marks respectively indicate the positive, attenuated, and negative localization of FAM83H mutants or CK1α to nuclear speckles (NS) in WiDr cells expressing the indicated mutants.
