Table 3 Stratified analysis of the correlation between prognostic nutritional index (PNI) and diabetic retinopathy (DR) in adults in the NHANES 2001–2018.

From: Association between prognostic nutritional index and diabetic retinopathy among U.S. diabetic adults in NHANES

Subgroup

Model OR (95%CI)

p-value

p for interaction

Age

  

0.469

 20–40

0.96(0.88,1.06)

0.459

 

 ≥ 40

0.93(0.90,0.96)

< 0.001

 

Gender

  

0.226

 Male

0.94(0.91,0.98)

0.002

 

 Female

0.92(0.88,0.95)

< 0.001

 

Race

  

0.673

 Mexican American

0.90 (0.86, 0.95)

< 0.001

 

 Other Hispanic

0.92(0.85, 1.00)

0.065

 

 Non-Hispanic White

0.93 (0.90, 0.97)

< 0.001

 

 Non-Hispanic Black

0.93 (0.90, 0.96)

< 0.001

 

 Other Race

0.96 (0.89, 1.05)

0.374

 

Marital status

  

0.896

 Married

0.94 (0.90, 0.98)

0.001

 

 Widowed

0.93 (0.87, 0.98)

0.016

 

 Divorced

0.95 (0.89, 1.01)

0.116

 

 Separated

0.91 (0.81, 1.02)

0.101

 

 Never married

0.90 (0.83, 0.98)

0.012

 

 Living with partner

0.90 (0.78, 1.03)

0.134

 

Education status

  

0.905

 Less Than 9th Grade

0.94 (0.89, 0.99)

0.022

 

 9-11th Grade

0.94 (0.88, 1.01)

0.098

 

 High School Grad

0.94 (0.90, 0.99)

0.031

 

 Some College or AA degree

0.92 (0.88, 0.97)

< 0.001

 

 College Graduate or above

0.91 (0.85, 0.97)

0.007

 

Smoking status

  

0.244

 YES

0.95 (0.90, 1.00)

0.046

 

 NO

0.95 (0.91, 1.00)

0.039

 

 Other

0.91 (0.88, 0.95)

< 0.001

 

Hypertension

  

0.307

 YES

0.92 (0.90, 0.95)

< 0.001

 

 NO

0.96 (0.91, 1.01)

0.078

 

 Other

0.79 (0.55, 1.13)

0.194

 

Alcohol drinking

  

0.162

 YES

0.97 (0.91, 1.03)

0.260

 

 NO

0.88 (0.82, 0.95)

0.001

 

 Other

0.93(0.90, 0.96)

< 0.001

 

Poverty-to-income ratio

  

0.178

 ≤ 1

0.91 (0.87, 0.95)

< 0.001

 

 1–3

0.95 (0.92, 0.98)

0.005

 

 > 3

0.93 (0.87, 0.98)

0.015

 

Diabetic nephropathy

  

0.822

 YES

0.94 (0.86,1.03)

0.206

 

 NO

0.94 (0.91, 0.97)

< 0.001

 

 Other

0.92 (0.86, 0.97)

0.005