Fig. 7
From: New benzimidazole-triazole glycoconjugates as anti-cancer agents and EGFR inhibitors
Physicochemical space for oral availability of compound 8a,b, 9a,b, 10a,b, erlotinib and Doxorubicin. LIPO (Lipophilicity), FLEX (Flexibility), INSOLU (Insolubility), INSATU (Unsaturation), and POLAR (Polarity) are key physicochemical properties. The pink-colored zone represents the optimal physicochemical space for oral bioavailability.
