Table 2 Multivariate analysis of factors associated with macular retinal layer thickness in eyes of normal participants (190 eyes of 124 participants).

From: Relationships between distance from the fovea to the disc and macular retinal layer thickness differ between normal and glaucomatous eyes

Variables

Macular RNFL

GCIPL

Outer retina

Coeff. [SE]

P value

Coeff. [SE]

P value

Coeff. [SE]

P value

FDD (mm)

– 3.14 [0.82]

0.0001*

– 0.83 [0.60]

0.17

– 2.38 [0.08]

0.08

Age (year)

0.04 [0.18]

0.18

– 0.08 [0.03]

0.010

– 0.16 [0.06]

0.013

Sex (male)

– 1.29 [0.54]

0.02

2.05 [0.55]

0.004

4.25 [1.25]

0.0007*

MD (dB)

0.13 (0.20)

0.50

0.07 [0.15]

0.63

– 0.02 [0.35]

0.96

Axial length (mm)

0.08 [0.29]

0.79

0.06 [0.26]

0.83

– 0.79 [0.57]

0.17

Corneal radius (mm)

– 0.69 [1.22]

0.57

– 0.22 [1.13]

0.85

– 1.10 [2.45]

0.65

Intraocular pressure (mmHg)

0.12 [0.11]

0.26

– 0.10 [0.10]

0.35

– 0.29 [0.23]

0.20

Disc area (mm2)

– 0.21 [0.53]

0.69

– 0.08 [0.36]

0.82

– 0.74 [0.82]

0.37

Ovality index

– 2.44 [1.65]

0.14

– 1.89 [1.10]

0.08

– 2.93 [2.52]

0.25

Torsion angle (degree)

0.006 [0.005]

0.23

0.001 [0.003]

0.70

0.01 [0.007]

0.04

FDA (degree)

– 0.03 [0.04]

0.45

– 0.005 [0.03]

0.83

0.02 [0.06]

0.74

Retinal artery angle (degree)

– 0.05 [0.01]

< 0.0001*

0.004 [0.007]

0.56

0.01 [0.02]

0.42

Average cpRNFL thickness (µm)

0.14 (0.02)

< 0.0001*

0.10 [0.02]

< 0.0001*

0.03 [0.04]

0.53

Image quality score

0.16 [0.03]

< 0.0001*

0.03 [0.02]

0.21

0.05 [0.06]

0.34

  1. P values were derived from mixed-effects models with all listed variables. Asterisks indicate p values < 0.05 after Bonferroni correction.
  2. cpRNFL circumpapillary retinal nerve fiber layer, GCIPL ganglion cell inner plexiform layer, Coeff. Coefficients, SE standard errors, FDD fovea-disc distance, MD mean deviation, FDA fovea-disc angle.
  3. Significant values are in bold.
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