Table 4 Differences in coefficients of fovea-disc distance for the association with macular retina layer thickness between normal and glaucomatous eyes (339 eyes of 241 patients).

From: Relationships between distance from the fovea to the disc and macular retinal layer thickness differ between normal and glaucomatous eyes

 

Macular RNFL

GCIPL

Outer retina

Coeff. [SE]

P value

Coeff. [SE]

P value

Coeff. [SE]

P value

FDD (Normal)

– 2.94 [0.84]

0.0004

– 1.11 [0.91]

0.22

– 2.52 [1.34]

0.06

FDD (Glaucoma)

– 3.34 [0.91]

0.0003

– 4.23 [1.00]

< 0.0001

– 3.75 [1.72]

0.03

P value (Normal vs. Glaucoma)

0.70

0.005

0.53

  1. A multivariate mixed-effects model accounting for correlation between fellow eyes in the same individuals was created for each macular retinal layer with explanatory variables including FDD, age, sex, MD, axial length, optic disc area, ovality index, optic disc torsion, FDA, retinal artery angle, cpRNFL thickness, and OCT image quality scores, and an interaction term between diagnosis (normal or glaucoma) and FDD. Only the coefficients for FDD for each group and the interaction term between diagnosis and FDD are shown in the table.
  2. RNFL retinal nerve fiber layer, GCIPL ganglion cell inner plexiform layer, Coeff. Coefficients, SE standard errors, FDD fovea-disc distance, MD mean deviation, FDA fovea-disc angle, cpRNFL circumpapillary RNFL.
  3. Significant values are in bold.