Fig. 3

Metabolomics analysis of liver in each group of mice. PCA plots: (A) (ND VS HFD), (B) (HFD VS HFD-ACT001), (C) (HFD VS FD-PPC).PLS-DA plots: (D) (ND VS HFD), (E) (HFD VS HFD-ACT001), (F) (HFD VS FD-PPC). The abscissa is the first principal component and the ordinate is the second principal component. Venn diagram (G), UPSET diagram (H) and bar diagram (I) of the comparison of differential metabolites in the positive and negative ion mode.