Fig. 7

Effect of TLR4/TLR2 inhibitors on ASPS-A1-induced activation of RAW 264.7 cells. (A,C, E, G) The levels of iNOS, TNF-α, IL-6, and IL-1β in the supernatant of RAW 264.7 cells were measured following treatment with C29; (B, D, F, H) The release of iNOS, TNF-α, IL-6, and IL-1β in the supernatant was assessed after treatment with TAK-242. The values are expressed as the means±SD (n=3). ns: not significant, *p < 0.05, **p < 0.01,***p < 0.001 and ****p < 0.0001.