Fig. 6 | Scientific Reports

Fig. 6

From: The role of the hippocampus and SLC39A8 in chronic musculoskeletal pain-induced dementia: a Mendelian randomization study

Fig. 6

Analysis of gene enrichment and protein–protein interactions. Multi-panel visualization of pathways linking pain and dementia. (A) Bar graph depicts enriched terms colored by P-values. (B) Network displays enriched terms clustered by similarity using cluster IDs. (C) Network highlights term significance with P-value-based coloring. (D) Overall PPI network (left) and a key MCODE component (right) reveal interactions involving HLA-DPB1 and COL6A5, indicating shared inflammatory mechanisms.

Back to article page