Fig. 2 | Scientific Reports

Fig. 2

From: Platelet-rich plasma relieves inflammation and pain by regulating M1/M2 macrophage polarization in knee osteoarthritis rats

Fig. 2

Effects of MIA and PRP on pain behavior. Intra-articular injection of 1 mg MIA significantly reduced the weight-bearing ability (A), PWT (B), and PWL (C) of the affected limb. After the injection of PRP, the weight-bearing (A), PWT (B), and PWL (C) of the affected limb increased. The arrows depict the time of injection of PRP. The bars represent the means ± SEMs (n = 6). ****p < 0.0001. Asterisks (*) denote differences between the Sham group and the MIA group. ##P < 0.01; ###P < 0.001; ####P < 0.0001. Hash signs (#) denote differences between the MIA group and the PRP group. PWT paw withdrawal latency, PWL paw withdrawal threshold.

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