Fig. 6
(a) The consensus matrixes for TCGA-LIHC cohorts based on the DEGs among the 2 HSCRGs clusters. TCGA samples were clustered into an appropriate number of subtypes (k = 3). (b) Kaplan–Meier curves showed an overall survival difference between gene clusters (p < 0.001). (c)The heatmap shows the expression of the hypoxia and senescence co-related DEGs in different HSCRGs clusters and gene clusters. (d) The difference of HSCRGs expression in different gene clusters. (e, f) GO and KEGG enrichment analysis of hypoxia and senescence co-related DEGs. DEGs, differentially expressed genes; HSCRGs, hypoxia-senescence co-related genes; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes(www.kegg.jp/kegg/kegg1.html). *P < 0.05, **P < 0.01, ***P < 0.001.
