Fig. 9

Schematic illustration of underlying physiological mechanisms regulating physiological hypoxia & thermal stress in fishes: Figure illustrating the overall mechanism of aquatic adaptation in response to hypoxic and thermal stress through the regulation of several genes that promote adipogenesis (hence as a result boosting mitochondrial biogenesis), myocyte differentiation, ETC regulation by degrading temperature-sensitive COX-IV isoform and inhibiting free radical formation.