Author Correction: Population structure and identification of genomic regions associated with productive traits in five Italian beef cattle breeds

Correction to: Scientific Reports https://doi.org/10.1038/s41598-024-59269-z, published online 12 April 2024

The original version of this Article contained errors. In the Results and discussion section, under the subheading ‘Genome-wide association study for productive traits’,

“The muscular hypertrophy phenotype segregates in the MAR breed due to a mutation at nucleotide 874 in exon 3 (g.874G > T) in the MSTN gene²⁷. This point mutation has a remarkable effect on the myostatin protein changing, a codon for glutamic acid into a stop codon (E291X variant), that blocks the translation of 254 bases of the third exon. The variant rs3423130174 (P-value 3.640819e−23) is indeed such causative mutation and confirms the implication of the third exon in the proper functioning of myostatin because it encodes the C-terminal region that is fundamental for the protein tridimensional folding²⁷.”

now reads:

“The muscular hypertrophy phenotype segregates in the MAR breed due to a mutation at nucleotide 871 in exon 3 (ENSBTAT00000015674.6:c.871G>T, represented by Ensembl sequence ENSBTAT00000015674.6) in the MSTN gene²⁷. This point mutation has a remarkable effect on the myostatin protein, changing a codon for glutamic acid into a stop codon (E291X variant) that blocks the translation of 257 bases of the third exon. The variant MSTN_SNP (P-value 3.640819e−23) is indeed such causative mutation and confirms the implication of the third exon in the proper functioning of myostatin because it encodes the C-terminal region that is fundamental for the protein tridimensional folding²⁷.”

Additionally, in Table 3, the position for Marchigiana breed in the top row was incorrect,

“rs3423130174 / 2 / 6283726 / T / 0.132 / 0.9037 / 0.0887 / 3.64E−23 / MSTN”

now reads:

“MSTN_SNP / 2 / 6283727 / T / 0.132 / 0.9037 / 0.0887 / 3.64E−23 / MSTN”.

As a result of this error, Figure 3 was incorrect. The original Figure 3 and accompanying legend appear below.

This correction does not affect the results and conclusions of this article.

The original Article has been corrected.

Fig. 3

Genome wide significant associations between SNPs and muscularity in Marchigiana breed. Negative log₁₀ P-values (Y-axis) of the association between SNPs and the muscularity are plotted against the genomic location of each SNP marker (X-axis). The red line represents the Bonferroni-corrected threshold of significance, while the blue line represents the suggestive threshold of significance (P-value of 0.05).