Fig. 1

Pyroptosis-related proteins are associated with SLC26A4 expression in PE-induced cardiac hypertrophy. (A–C) The mRNA expression of ANP (A), β-MHC (B) and BNP (C) was detected in PE-induced cardiomyocyte by RT-qPCR. (D) representative images of cardiac hypertrophy, as shown by α-SMA immunofluorescence. The nucleus was stained with DAPI (blue); the scale bar represents 100 μm. (E–H) The mRNA expression of SLC26A4 (E), ASC (F), NLRP3 (G) and caspase-1 (H) was detected in PE-induced cardiomyocyte by RT-qPCR. I: The protein expression of ACS, NLRP3, and caspase-1 was detected in PE-induced cardiac hypertrophy by Western blotting (^*P < 0.05, ^**P < 0.01, ^***P < 0.001 vs. normal group; Results were analyzed by one-way ANOVA, Protein bands were cut from different sites).