Fig. 5

Animal model validation and HE staining observation of heart tissue. (A–C): The relative expression of ANP (A), BNP (B) and β-MHC (C) in SD rat heart tissues was detected by RT-qPCR; (D): Heart-to-weight ratio in SD rats; (E): HE staining observation of heart tissue. (*P < 0.05, **P < 0.01, ***P < 0.001 vs. normal group; Five rats were used in each group, and the results were analyzed by one-way ANOVA).