Fig. 5
From: Comparison of 18F-FDG and 68Ga-DOTA-IBA in detecting bone metastases: a lesion-basis study
Images of a 46-year-old woman diagnosed with lung carcinoma who underwent 18F-FDG examinations for initial staging. (a) The maximum intensity projection (MIP) image of 18F-FDG showed moderate-low radiotracer uptake in the right pelvis (arrows, SUVmax=3.9) and left head of the femur (arrowheads, SUVmax=2.4). (b) The maximum intensity projection (MIP) image of 68Ga-DOTA-IBA demonstrated obvious radiotracer uptake in the right pelvis (arrows, SUVmax=13.6) and left head of the femur (arrowheads, SUVmax=9.2). (c,d) Axial fusion images of a mixed type of lesion showed that it is negative on 18F-FDG and positive on 68Ga-DOTA-IBA (curved arrow, SUVmax=2.5 vs. 8.0). CT showed osteogenic bone changes at the corresponding sites. Follow-up imaging 3 months later confirmed the presence of these bone metastases. 68Ga-DOTA-IBA, gallium 68 (68Ga)-labeled DOTA-conjugate ibandronic acid; 18F-FDG, fluorine 18 (18F)-labeled fluorodeoxyglucose.
