Fig. 6
From: Comparison of 18F-FDG and 68Ga-DOTA-IBA in detecting bone metastases: a lesion-basis study
Images of a 52-year-old woman diagnosed with lung carcinoma treated by surgery who underwent 18F-FDG examinations for restaging. (a) The maximum intensity projection (MIP) image of 18F-FDG showed obvious radiotracer uptake in multiple vertebras (arrowheads, mean SUVmax=5.7) and right ribs (arrows, SUVmax=6.2). (b) The maximum intensity projection (MIP) image of 68Ga-DOTA-IBA also demonstrated obvious radiotracer uptake in multiple vertebras (arrowheads, mean SUVmax=19.4) and right ribs (arrows, SUVmax=12.0). (c,d) Axial fusion images of an osteoblastic lesion showed that it is negative on 18F-FDG and positive on 68Ga-DOTA-IBA (curved arrow, SUVmax=2.9 vs. 14.7). CT showed osteogenic bone changes at the corresponding sites. Follow-up imaging 3 months later confirmed the presence of these bone metastases. 68Ga-DOTA-IBA, gallium 68 (68Ga)-labeled DOTA-conjugate ibandronic acid; 18F-FDG, fluorine 18 (18F)-labeled fluorodeoxyglucose.
