Table 3 Comparison of diagnostic performance of lesions from different sites.
From: Comparison of 18F-FDG and 68Ga-DOTA-IBA in detecting bone metastases: a lesion-basis study
Site | Tracer | No. of positive lesions | Sensitivity | 95% CI | p# |
|---|---|---|---|---|---|
Limbs | 18F-FDG | 98 | 64.1%(98/153) | 0.56–0.72 | 0.024 |
68Ga-DOTA-IBA | 112 | 73.2%(112/153) | 0.66–0.8 | ||
Vertebras | 18F-FDG | 327 | 67.4%(327/485) | 0.63–0.72 | < 0.001 |
68Ga-DOTA-IBA | 379 | 78.1%(379/485) | 0.74–0.82 | ||
Ribs | 18F-FDG | 130 | 62.2%(130/209) | 0.56–0.69 | < 0.001 |
68Ga-DOTA-IBA | 181 | 86.6%(181/209) | 0.82–0.91 | ||
Pelvis | 18F-FDG | 142 | 68.9%(142/206) | 0.63–0.75 | 0.019 |
68Ga-DOTA-IBA | 162 | 78.6%(162/206) | 0.73–0.84 | ||
Skulls | 18F-FDG | 19 | 38%(19/50) | 0.25–0.51 | < 0.001 |
68Ga-DOTA-IBA | 40 | 80.0%(40/50) | 0.69–0.91 | ||
Total | 18F-FDG | 716 | 64.9%(716/1103) | 0.62–0.68 | < 0.001 |
68Ga-DOTA-IBA | 874 | 79.2%(874/1103) | 0.77–0.82 |
