Table 4 Comparison of diagnostic performance detecting lesions of different types.

From: Comparison of 18F-FDG and 68Ga-DOTA-IBA in detecting bone metastases: a lesion-basis study

Major lesions’ type

N*

Tracer

No. of positive lesions

Sensitivity

95% CI

P#

Osteoblastic

23

18F-FDG

327

51.5%(327/635)

0.48–0.55

< 0.001

68Ga-DOTA-IBA

529

83.3%(529/635)

0.80–0.86

Osteolytic

13

18F-FDG

180

79.6%(180/226)

0.74–0.85

0.533

68Ga-DOTA-IBA

185

81.9%(185/226)

0.77–0.87

  1. *Number of participants.
  2. #McNemar test.
  3. Numbers in paratheses are number of lesions to calculate the ratio.
  4. CI, confidence interval.
  5. 68Ga-DOTA-IBA, gallium 68 (68Ga)-labeled DOTA-conjugate ibandronic acid;18F-FDG, fluorine 1818F)-labeled fluorodeoxyglucose.
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