Fig. 2 | Scientific Reports

Fig. 2

From: Marein from Coreopsis tinctoria Nutt. alleviates oxidative stress and lipid accumulation via SIRT1/Nrf2 signaling

Fig. 2

Marein suppressed H2O2-induced lipid metabolism disorders in HepG2 cells. HepG2 cells were exposed 500μM H2O2 condition for 24h, and then administrated by 5 μM Marein for another 24h. (a–d) Determination of TC (a), TG (b), LDL-C (c), and HDL-C (d) by ELISA. (e, f) Detection of lipid metabolism related genes HMGCR (e) and LDLR (f) by RT-qPCR. (g) Western blot analysis of HMGCR and LDLR protein levels. Values were expressed as mean ± SD of three separate determinations. *P < 0.05, **P < 0.01, ***P < 0.001.

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