Fig. 3 | Scientific Reports

Fig. 3

From: PRC1 as an independent adverse prognostic factor in Wilms tumor via integrated bioinformatics and experimental validation

Fig. 3

Immunological characteristic analysis based on PRC1 expression in WT. (A) CIBERSORT analysis comparing 22 types of immune cell types between high and low PRC1 expression groups in WT. (B) Tumor Microenvironment (TME) Scores by ESTIMATE analysis between high and low PRC1 expression groups in WT. (C) Correlation analysis using Spearman method between PRC1 mRNA levels and 22 types of immune cells. (D) Scatter plot depicting the negative correlation between PRC1 expression and the number of activated NK cells (r = -0.63, p < 0.05). (E) Gene Set Enrichment Analysis (GSEA) using the ‘c7.immunesigdb.v2024.1.Hs.symbols.gmt’ gene set to analyze PRC1 expression in NK cells.

Back to article page