Fig. 5
Annotation of the different cell clusters and functional enrichment analysis of Cancer cells. (A) Bubble plots showing mRNA expression levels of marker genes for each cell type. (B, C) 11 cell types were annotated based on marker gene expression and information from other databases. The annotation results were visualized using t-SNE and UMAP plots. (D) Distribution of PRC1 expression in different cell types by UMAP plots. (E) Heatmap displaying specific gene expression in each cell type. (F, G) Comparison of PRC1 expression levels in cancer cells and NK cells between AWT and FWT groups. (H) Functional enrichment analysis of hallmark gene sets was performed on cancer cells with high and low PRC1 expression groups. (I, J) GO and KEGG enrichment analysis was performed on cancer cells with high and low PRC1 expression groups.
