Fig. 6 | Scientific Reports

Fig. 6

From: AJUBA promotes the proliferation, invasion and migration of NSCLC cells by activating the ERK/β-catenin pathway

Fig. 6

Downregulation of AJUBA inhibits the growth of NSCLC cells in vivo. (A) Image of tumors in nude mouse tissues from the two groups. (B) Tumor volume in the shctrl and shAJUBA groups. Two-tailed Student’s t-test was used to analyze the differences between the two groups. ***P < 0.001. (C) The tumor weights in the NSCLC mouse model were measured in the shctrl and shAJUBA groups. Two-tailed Student’s t-test was used to analyze the differences between the two groups. ***P < 0.001. (D) The expression levels of AJUBA, Ki67, p-ERK, β-catenin and N-cadherin were investigated in control and AJUBA-depleted groups by IHC (200X).

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