Table 1 Clinical characteristics of patients with NLE complicated by CHB.

From: Clinical characteristics of neonatal lupus erythematosus complicated by congenital heart block: a multi-center retrospective study in East China

Parameters

NLE (n = 91)

CHB (n = 15)

No-CHB (n = 76)

P

Sex

 Male

37 (40.66)

6(4.00)

31(40.79)

0.995

 Female

54 (59.34)

9(6.00)

45(59.21)

 Gestational age (weeks)

37 ± 2

(36 ± 1, 38 ± 4)

37

(35 ± 2, 38 ± 4)

37 ± 4

(36 ± 2, 38 ± 6)

0.291

 Birth weight (g)

2510.35

(1960.20, 3104.30)

2500.30

(1910.00, 3075.40)

2570.50

(2050.60, 3120.90)

0.410

Mode of delivery

 Cesarean section

40 (43.96)

7(46.67)

33(43.42)

0.817

 Vaginal delivery

51 (56.04)

8(53.33)

43(56.58)

 Maternal allergic diseases

38 (41.75)

10(66.67)

28(36.84)

0.032

Maternal autoimmune disorders

 Systemic lupus erythematosus

51 (56.04)

9(60.00)

42(55.26)

0.736

 Photosensitivity symptoms

10 (10.99)

0(0.00)

10(13.16)

0.149

 Mixed connective tissue disease syndrome

4 (4.40)

2(13.33)

2(2.63)

0.247

 Sjögren’s Disease Syndrome

8 (8.79)

1(6.67)

7(9.21)

1.000

 Abnormal autoantibodies

9 (9.89)

2(13.33)

7(9.21)

0.988

 No autoimmune disease

9 (14.29)

1(6.67)

8(10.53)

1.000

 Pregnancy-associated lupus flare

7 (7.69)

3(20.00)

4(5.26)

0.153

  1. NLE, neonatal lupus erythematosus; CHB, congenital heart block.