Fig. 1
Association between IS indices and BMI-related genetic variants. The left panel shows analyses adjusted for age, sex, and BMI, while the right panel shows analyses adjusted for age and sex only. All displayed associations are nominally significant (p < 0.05), highlighting variants linked to increased BMI. Variants are grouped using k-means clustering to demonstrate positive and negative effects on IS indices. The x-axis categorizes IS indices based on calculation time points (fasting, OGTT0,120, and OGTT0,30,120), and the y-axis lists genes, variants (rsIDs), and BMI-increasing alleles. Significance levels are indicated by asterisks: *padj < 0.05 and **padj < 0.01.
