Fig. 2
Venn diagrams illustrate the summary of the insulin sensitivity (IS)-associated genetic variants across different IS indices, comparing fasting indices (blue), OGTT0,120 (green), and OGTT0,30,120 (red). Variants are also labelled based on their association with increased (IS +) or decreased (IS -) insulin sensitivity. (A) BMI-associated variants in both sexes combined. (B) WHR-associated variants association in females. (C) WHR-associated variants association in males. Adjusted models (left column) accounting for BMI, while unadjusted models (right column) do not. The genetic variants displayed in each panel indicate loci associated with insulin sensitivity indices within each group. Missing circles indicate that no association was observed in the respective model.
