Table 5 Overview of miRNA biomolecules of differentially expressed genes of tuberculosis.

hsa-mir-383-3p

MicroRNA 383

Inhibitor of tumors in several different cancer types, such as thyroid, kidney, and cervical cancer¹

hsa-mir-520 h

MicroRNA 520 h

Downregulated Death-associated protein kinase 2 (DAPK2) expression² , and decrease of side population cells and prevention of cell propagation and invasion in PANC1 cell line³

hsa-mir-520 g-3p

MicroRNA 520 g

Associated with reduced procoagulant and signaling potential of cancer cells⁴

hsa-mir-7977

MicroRNA 7977

Novel indicator to patients of lung adenocarcinoma and may play as tumor suppressor in lung cancer⁵

hsa-mir-218-5p

MicroRNA 218–1

Has a vital function in preventing lung cancer cells from proliferating and migrating, most likely by attaching to the EGFR receptor⁶

hsa-mir-6499-3p

MicroRNA 6499 3p

MiR-6499-3p was predicted to target the NFKBIA gene. NFKBIA has a role in the acute stage responsive signaling, which includes T and neutrophil activation⁷

hsa-mir-30a-5p

MicroRNA 30a

Increases paclitaxel (lung cancer cell) sensitivity by suppressing BCL-2, a crucial apoptosis regulator, thus encouraging chemotherapy-induced apoptosis⁸

hsa-let-7b-5p

MicroRNA Let-7b

Prohibits the Transportation and poliferation of growth factor derived from platelets (PDGF) triggered Pulmonary Artery Smooth Muscle Cells (PASMCs) by modulating IGF1⁹

hsa-mir-26b-5p

MicroRNA 26b

Enhanced apoptosis, decreased fibroblasts, and reduced lung fibrosis in mice bronchial tissues, and decreased mortality in mouse bronchial tissues due to upregulation of miR-26a-5p¹⁰

hsa-mir-27a-3p

MicroRNA 27a

Lung fibroblast development into myofibroblasts was boosted by miR-27a-3p suppression, while overexpression was hindered¹¹

hsa-mir-129–2-3p

MicroRNA 129–2

Members of the MiR-129 family are widely acknowledged to be tumor suppressors, exhibiting reduced expression in several types of cancers¹²

hsa-mir-34a-5p

MicroRNA 34a

In the p53 wild-type tumor in the colon cell HCT116, miR-34a-5p markedly reduced cell proliferation, migration, invasion, and metastasis¹³

hsa-mir-1-3p

MicroRNA 1–1

Had a restraint effect on the tumorigenic potential of lung adenocarcinoma (LUAD) cells, as demonstrated by the markedly decreased vitality, movement, and incursion of LUAD cells upon miR-1-3p upregulation. Furthermore, miR-1-3p showed conspicuous downregulation in human cell lines and LUAD tissues¹⁴

hsa-mir-16-5p

MicroRNA 16–1

Since miR-16-5p is not highly expressed in breast cancer tissues, it can prevent breast cancer by inhibiting the NF-κ B pathway and raising the level of AKT3¹⁵

hsa-mir-124-3p

MicroRNA 124–3

miR-124 expression at a low level in breast cancer tissue was linked to poor prognosis of patients¹⁶

hsa-let-7b-5p

MicroRNA Let-7b

hsa-let-7b-5p may prevent glioma cells from migrating, invading, and going through cell cycle¹⁷