Table 3 Description of biomarkers characteristics.

From: Personal exposure to air pollutants and immune system biomarkers in pregnant women

Cytokine levels

Percentile of raw values

Percentile of imputed, corrected and log10 transformed values

N

10%

25%

50%

75%

90%

10%

25%

50%

75%

90%

IQR

Concentration of leucocytes (G/L)

265

6.8

7.6

8.9

10.2

11.6

      

At basal state

  IL-8 (pg/mL)

266

5.5

8.9

17.8

94.3

283.1

0.50

0.84

1.07

1.36

1.86

0.52

  MCP1 (pg/mL)

266

19.0

25.9

38.4

56.2

116.0

1.22

1.38

1.51

1.64

1.77

0.26

  RANTES (pg/mL)

266

7374.1

9873.3

14,026.3

17,511.4

23,935.5

3.84

3.96

4.08

4.16

4.24

0.20

After PHA activation

  IFN-γ (pg/mL)

264

300.0

429.7

758.4

1383.8

3121.9

2.60

2.75

2.94

3.14

3.30

0.39

  IL-2 (pg/mL)

264

1067.1

1701.6

2664.7

4245.8

7877.3

3.13

3.30

3.47

3.65

3.78

0.35

  IL-9 (pg/mL)

264

13.8

20.7

35.8

59.7

86.8

1.29

1.45

1.64

1.85

2.05

0.40

  IL-10 (pg/mL)

264

428.4

609.1

904.3

1369.6

2428.1

2.76

2.91

3.04

3.18

3.30

0.27

  IL-13 (pg/mL)

264

57.1

83.9

138.1

205.8

339.4

1.75

1.93

2.11

2.26

2.40

0.33

  IL-17A (pg/mL)

259

94.0

156.6

282.0

518.6

1151.4

2.15

2.32

2.55

2.78

2.97

0.43

  TNF-α (pg/mL)

264

12.8

247.9

760.2

1468.2

2489.4

1.38

2.22

2.70

2.97

3.22

0.75

After R848 activation

  IFN-α (pg/mL)

270

41.6

116.7

259.2

573.1

976.9

2.20

2.39

2.68

2.92

3.12

0.53

  IFN-γ (pg/mL)

270

82.3

173.0

366.8

738.5

1211.7

1.93

2.24

2.60

2.89

3.16

0.65

  IL-1β (pg/mL)

270

4503.4

6481.8

9157.4

13,545.0

19,700.1

3.60

3.73

3.88

4.02

4.15

0.29

  IL-6 (pg/mL)

270

21,720.3

32,069.2

44,667.9

60,509.2

87,701.3

4.26

4.40

4.54

4.66

4.79

0.26

  IL-8 (pg/mL)

270

12,534.4

20,895.5

39,810.9

66,939.8

112,322.1

3.93

4.10

4.35

4.54

4.76

0.44

  IL-10 (pg/mL)

270

348.4

530.7

782.9

1090.5

1348.7

2.51

2.66

2.79

2.91

3.05

0.25

  IL-12p70 (pg/mL)

270

7.1

11.7

22.5

37.5

61.0

0.87

1.11

1.35

1.59

1.79

0.48

  TNF-α (pg/mL)

270

116.3

2643.8

6382.1

11,480.7

15,127.2

1.84

2.82

3.21

3.44

3.66

0,62

  1. Abbreviations: IL, interleukin; IFN interferon; TNF tumor necrosis factor; RANTES regulated on activation, normal T cell expressed and secreted; MCP monocyte chemoattractant protein; PHA phytohemagglutinin; R848 resiquimod.