Fig. 5

Tissue immunofluorescence was used to detect the role of SIRT1 in osteoclast differentiation. (A,B), Expression and fluorescence intensity statistics of SIRT1 in the tissues of teeth with hypofunctional occlusion after 2, 3 and 4 weeks of treatment. (C,D), Expression and fluorescence intensity statistics of β-catenin in the tissues of teeth with hypofunctional occlusion after 2, 3 and 4 weeks of treatment. All the data are expressed as the means ± SEMs (two-way ANOVA was followed by Šídák’s multiple comparisons test; #P < 0.05 vs. Control; *P < 0.05 vs. Hypo).