Table 9 The results of PDmax, AUEC0 − t bidirectional unilateral t-test, and [1–2α] confidence interval method for Beta2-microglobulin (BES, N = 12).

From: Investigation into the pharmacodynamics and pharmacokinetics of recombinant human interferon alfa-2b vaginal suppository following process optimization in chinese rhesus macaque

Parameter

t-value

P-value

Geometric mean and ratio (N = 12)

Individual variability %CV of subjects

90% CI

Compared to the lower limit tL

Compared to the high limit tH

Compared to the lower limit PL

Compared to the high limit PH

Sample R

Sample S

(S/R) %

PDmax (mg/L)

13.74

-13.66

0.0000

0.0000

1.63

1.63

100.07

3.99

97.16%~103.07%

AUEC0 − t (mg∙h/L)

15.80

-17.43

0.0000

0.0000

91.03

90.04

98.91

3.29

96.53%~101.34%