Fig. 4 | Scientific Reports

Fig. 4

From: Integrated spatial and single cell transcriptomics identifies PRKDC as a dual prognostic biomarker and therapeutic target in hepatocellular carcinoma

Fig. 4

Relationship of PRKDC expression with spatial transcriptomics of HCC. (A) Spatial transcriptomics analysis of hepatocellular carcinoma HCC tissue. (B) Spatial distribution of various immune and stromal cell subtypes in the HCC tumor microenvironment. (C) Spatial expression of PRKDC in the HCC tissue. (D) Spatial segmentation of malignant, normal, and mixed tissue regions. (E) Quantitative analysis of PRKDC expression across malignant, mixed, and normal tissue regions. (F) Correlation analysis between PRKDC expression and various immune and stromal cell subtypes. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns > 0.05.

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