Fig. 1

Effects of HFD and CRS on the anxiety and depression-like behaviors. (A) Schematic diagram of mice dealing with HFD and CRS. (B) Body weight of mice. (C) Total fluid intake test (FIT) for SPT. (D) The percentage of sucrose consumption in the SPT. (E) Immobility time was determined in the FST. (F) Immobility time was determined in the TST. Data were expressed as mean ± SEM (n = 8), *p < 0.05, **p < 0.01, ***p < 0.001 vs. control group; #p < 0.05, ##p < 0.01, ###p < 0.001 vs. CRS group; $p < 0.05, $$p < 0.01, $$$p < 0.001 vs. HFD group.