Fig. 2

Effects of HFD and CRS on the anxiety behaviors. (A) Representative locomotion trajectories of OFT. (B) Ambulatory distance in the OFT. (C) Time in the center zone in the OFT. Data were expressed as mean ± SEM (n = 8), *p < 0.05, **p < 0.01, ***p < 0.001 vs. control group; #p < 0.05, ##p < 0.01, ###p < 0.001 vs. CRS group; $p < 0.05, $$p < 0.01, $$$p < 0.001 vs. HFD group.