Table 2 Cross-ancestry replication of significant metabolites from the Diabetes Heart Study (DHS) MIND European American (EA) discovery cohort in the African American (AA) DHS MIND African American discovery cohort. Results are grouped by cognitive test. For each metabolite the biochemical name and associated super- and sub-pathways are listed. Biochemicals with an * before their name indicate metabolites not detected in more than 50% of participants and were analyzed as both continuous and binary measures (dichotomized as detectable vs. non-detectable). From the statistical analysis, the effect estimate, standard error (SE), nominal p-value (P), and FDR-corrected p-value (P_FDR) are provided.

From: Metabolomic signatures of cognitive function in a type 2 Diabetes-Enriched cohort