Table 2 The secondary structural changes of the α-glucosidase in the absence and presence of compound 14b.

From: 1-Phenyl-β-carboline-3-carboxamide-1,2,3-triazole-N-phenylacetamide hybrids as new α-glucosidase inhibitors

Molar ratio [α-Glu]: [Compound 14b]

α-Helix (%)

β-Sheet (%)

β-Turn (%)

Random coil (%)

1:0

9.40

38.40

19.50

35.40

1:1

12.95

31.75

19.45

34.55

1:2

11.56

34.14

19.34

34.66