Table 3 Comparisons of clinical indicators before NAC.NICB between the patients achieved pCR and the non-pCR groups.

From: Real-world comparison of neoadjuvant chemoimmunotherapy and chemotherapy in muscle-invasive bladder cancer

 

pCR (N = 14)

Non-pCR (N = 15)

P value

Clinical stage

  

> 0.999c

=T2N0M0

3(21.4%)

4(26.7%)

 

> T2N0M0

11(78.6%)

11(73.3%)

 

RBC (*10^12/L)†

4.06 ± 0.76

4.56 ± 0.77

0.087a

Hb (g/L)††

132.5(117.0-151.3)

115.0(109.0-127.0)

0.018*b

Platelet (*10^9/L)††

187.0(148.0-208.3)

243.0(188.0-333.0)

0.026*b

Neutrophil (*10^9/L)††

3.95(3.73–4.28)

3.82(3.27–6.21)

0.983b

Lymphocyte (*10^9/L)†

1.31 ± 0.60

1.51 ± 0.58

0.383a

NLR (%)††

3.25(2.22–5.46)

3.02(2.13–4.24)

0.652b

PLR (%)†

179.40 ± 87.63

184.24 ± 86.51

0.882a

Albumin (g/L)†

39.54 ± 4.81

40.69 ± 4.53

0.531a

ALG (%)†

1.33 ± 0.29

1.28 ± 0.15

0.577a

  1. NAC.NICB: neoadjuvant chemotherapy combined with immune checkpoint blockade; pCR: pathological complete response; RBC: Red Blood Cell; Hb: hemoglobin; NLR: Neutrophil to Lymphocyte Ratio; PLR: Platelet to Lymphocyte Ratio; ALG: Albumin/Globulin Ratio; ICB: Immune Checkpoint Blockade.
  2. †Data are presented as mean ± SD.
  3. ††Data are presented as median (25th-75th percentile).
  4. aTwo-sample t-tests.
  5. bMann–Whitney U-Test.
  6. cFisher’s exact test.
  7. *P < 0.05 was recognized as statistically different.