Table 3 Assessment of chemosensitivity in (Caco2) cell lines utilizing the MTT assay through half-log concentration dilutions. This table indicates that the results were represented as IC50, which refers to the concentration of the cytotoxic drug that decreases cell viability by 50% compared to the control.
ID | µg/mL | O.D | Mean O.D | ±SEM | Viability % | Toxicity % | IC50 ± SD | ||
|---|---|---|---|---|---|---|---|---|---|
Caco2 | – | 0.66 | 0.67 | 0.674 | 0.668 | 0.0042 | 100 | 0 | µg/mL |
DMSO | 300 | 0.525 | 0.518 | 0.506 | 0.516333 | 0.0055 | 72.0130172 | 27.9869828 | |
Doxo. | 300 | 0.02 | 0.02 | 0.02 | 0.02 | 0 | 2.789400279 | 97.21059972 | 16.49 ± 0.09 |
100 | 0.02 | 0.023 | 0.021 | 0.021333 | 0.0009 | 2.975360298 | 97.0246397 | ||
30 | 0.146 | 0.151 | 0.138 | 0.145 | 0.0038 | 20.22315202 | 79.77684798 | ||
10 | 0.355 | 0.359 | 0.367 | 0.360333 | 0.0035 | 50.25569503 | 49.74430497 | ||
3 | 0.721 | 0.71 | 0.716 | 0.715667 | 0.0032 | 99.81403998 | 0.185960019 | ||
1 | 0.718 | 0.714 | 0.719 | 0.717 | 0.0015 | 100 | 0 | ||
0.31 | 0.72 | 0.714 | 0.717 | 0.717 | 0.0017 | 100 | 0 | ||
CUR | 300 | 0.018 | 0.018 | 0.017 | 0.017667 | 0.0003 | 2.644710579 | 97.35528942 | 9.34 ± 0.04 |
100 | 0.022 | 0.019 | 0.023 | 0.021333 | 0.0012 | 3.193612774 | 96.80638723 | ||
30 | 0.086 | 0.093 | 0.087 | 0.088667 | 0.0022 | 13.27345309 | 86.72654691 | ||
10 | 0.298 | 0.31 | 0.307 | 0.305 | 0.0036 | 45.65868263 | 54.34131737 | ||
3 | 0.616 | 0.597 | 0.606 | 0.606333 | 0.0055 | 90.76846307 | 9.231536926 | ||
1 | 0.671 | 0.664 | 0.668 | 0.667667 | 0.0020 | 99.9500998 | 0.0499002 | ||
0.3 | 0.67 | 0.669 | 0.665 | 0.668 | 0.0015 | 100 | 0 | ||
CUR-Liposomes | 300 | 0.026 | 0.025 | 0.027 | 0.026 | 0.0006 | 3.892215569 | 96.10778443 | 2.44 ± 0.01 |
100 | 0.021 | 0.025 | 0.024 | 0.023333 | 0.0012 | 3.493013972 | 96.50698603 | ||
30 | 0.02 | 0.024 | 0.023 | 0.022333 | 0.0012 | 3.343313373 | 96.65668663 | ||
10 | 0.074 | 0.055 | 0.058 | 0.062333 | 0.0059 | 9.331337325 | 90.66866267 | ||
3 | 0.254 | 0.269 | 0.273 | 0.265333 | 0.0058 | 39.72055888 | 60.27944112 | ||
1 | 0.517 | 0.505 | 0.508 | 0.51 | 0.0036 | 76.34730539 | 23.65269461 | ||
0.3 | 0.653 | 0.659 | 0.663 | 0.658333 | 0.0029 | 98.55289421 | 1.447105788 | ||