Table 3 Assessment of chemosensitivity in (Caco2) cell lines utilizing the MTT assay through half-log concentration dilutions. This table indicates that the results were represented as IC50, which refers to the concentration of the cytotoxic drug that decreases cell viability by 50% compared to the control.

From: Comparative in vitro cytotoxicity of free curcumin and a liposomal curcumin formulation on various human cancer cell lines

ID

µg/mL

O.D

Mean O.D

±SEM

Viability %

Toxicity %

IC50 ± SD

Caco2

0.66

0.67

0.674

0.668

0.0042

100

0

µg/mL

DMSO

300

0.525

0.518

0.506

0.516333

0.0055

72.0130172

27.9869828

 

Doxo.

300

0.02

0.02

0.02

0.02

0

2.789400279

97.21059972

16.49 ± 0.09

100

0.02

0.023

0.021

0.021333

0.0009

2.975360298

97.0246397

30

0.146

0.151

0.138

0.145

0.0038

20.22315202

79.77684798

10

0.355

0.359

0.367

0.360333

0.0035

50.25569503

49.74430497

3

0.721

0.71

0.716

0.715667

0.0032

99.81403998

0.185960019

1

0.718

0.714

0.719

0.717

0.0015

100

0

0.31

0.72

0.714

0.717

0.717

0.0017

100

0

CUR

300

0.018

0.018

0.017

0.017667

0.0003

2.644710579

97.35528942

9.34 ± 0.04

100

0.022

0.019

0.023

0.021333

0.0012

3.193612774

96.80638723

30

0.086

0.093

0.087

0.088667

0.0022

13.27345309

86.72654691

10

0.298

0.31

0.307

0.305

0.0036

45.65868263

54.34131737

3

0.616

0.597

0.606

0.606333

0.0055

90.76846307

9.231536926

1

0.671

0.664

0.668

0.667667

0.0020

99.9500998

0.0499002

0.3

0.67

0.669

0.665

0.668

0.0015

100

0

CUR-Liposomes

300

0.026

0.025

0.027

0.026

0.0006

3.892215569

96.10778443

2.44 ± 0.01

100

0.021

0.025

0.024

0.023333

0.0012

3.493013972

96.50698603

30

0.02

0.024

0.023

0.022333

0.0012

3.343313373

96.65668663

10

0.074

0.055

0.058

0.062333

0.0059

9.331337325

90.66866267

3

0.254

0.269

0.273

0.265333

0.0058

39.72055888

60.27944112

1

0.517

0.505

0.508

0.51

0.0036

76.34730539

23.65269461

0.3

0.653

0.659

0.663

0.658333

0.0029

98.55289421

1.447105788