Fig. 2 | Scientific Reports

Fig. 2

From: Longitudinal and cross-sectional associations of myocardial stress markers with kidney function and chronic kidney disease in the BiomarCaRE project

Fig. 2

Longitudinal associations of NT-proBNP with 10-year change in kidney function. Linear mixed-effects model was used to estimate beta coefficients and 95% CI of the change in eGFR for G2-4 compared with G1 of NT-proBNP, as well as for per 1 SD increase in log-transformed NT-proBNP. The follow-up duration was used as a timescale and divided by 10 to give a 10-year change. Detailed information on adjusted models is described in Table 4. A maximum of 4205 participants with 10,208 observations were included in these analyses. Categories of NT-proBNP: G1: < 48; G2: 48–125; G3: 125–300; G4: ≥ 300 pg/ml. CI, confidence interval; G, group; eGFR, estimated glomerular filtration rate; eGFRcr, creatinine-based eGFR; eGFRcys, cystatin C-based eGFR; eGFRcr-cys, creatinine and cystatin C-based eGFR; NT-proBNP, N-terminal pro-B-type natriuretic peptide; SD, standard deviation; * p < 0.05, ** p < 0.01, *** p < 0.001.

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