Fig. 3 | Scientific Reports

Fig. 3

From: Longitudinal and cross-sectional associations of myocardial stress markers with kidney function and chronic kidney disease in the BiomarCaRE project

Fig. 3

Longitudinal associations of NT-proBNP with incident CKD. Interval-censored Cox regression was used to estimate HR and 95% CI (1000 bootstrap samples for 95% CI estimation) of incident CKD for G2-4 compared with G1 of NT-proBNP, as well as for per 1 SD increase in log-transformed NT-proBNP. A total of 4167 participants free of CKDcr, 2557 free of CKDcys, and 2621 free of CKDcr-cys at baseline were included in these analyses. Detailed results are presented in Table S9. Categories of NT-proBNP: G1: < 48; G2: 48–125; G3: 125–300; G4: ≥ 300 pg/ml. CI, confidence interval; CKD, chronic kidney disease; CKDcr, creatinine-based CKD; CKDcys, cystatin C-based CKD; CKDcr-cys, creatinine and cystatin C-based CKD; G, group; HR, hazard ratio; NT-proBNP, N-terminal pro-B-type natriuretic peptide; SD, standard deviation; * p < 0.05, ** p < 0.01, *** p < 0.001.

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