Fig. 4

Cross-sectional associations of 3 myocardial stress markers with kidney function stratified by CVD and diabetes. Interaction terms of standardized log-transformed markers with CVD or diabetes were included in linear regression, applying model 2 described in Table 2, to test the significance of interaction. Data from 61,830 participants for NT-proBNP, 9499 for MR-proANP, and 9327 for MR-proADM were included in these analyses. Please refer to Table S10-12 for detailed results. CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; eGFRcr, creatinine-based eGFR; eGFRcys, cystatin C-based eGFR; eGFRcr-cys, creatinine and cystatin C-based eGFR; MR-proADM, mid-regional pro-adrenomedullin; MR-proANP, mid-regional pro-atrial natriuretic peptide; NT-proBNP, N-terminal pro-B-type natriuretic peptide; SD, standard deviation; ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001.