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Classification of paroxysmal atrial fibrillation using sinus rhythm electrocardiograms using the symmetric projection attractor reconstruction method
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  • Published: 18 February 2026

Classification of paroxysmal atrial fibrillation using sinus rhythm electrocardiograms using the symmetric projection attractor reconstruction method

  • Steven Creasy1,2,
  • Gregory Y. H. Lip3,4,
  • Gary Tse5,6,7,
  • Manasi Nandi8,
  • Kamalan Jeevaratnam1 &
  • …
  • Philip J. Aston2 

Scientific Reports , Article number:  (2026) Cite this article

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We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Cardiology
  • Computational biology and bioinformatics
  • Diseases
  • Medical research

Abstract

Atrial fibrillation is the most commonly encountered cardiac arrhythmia, increasing stroke risk and mortality. Paroxysmal atrial fibrillation (PAF) can be challenging to detect because arrhythmias occur intermittently. We have been able to classify PAF patients from sinus rhythm electrocardiograms (ECG), using a signal processing technique, Symmetric Projector Attractor Reconstruction, which transforms the ECG time-series into a quantifiable two-dimensional image termed an attractor. To optimise this methodology, we investigated the impact of varying parameters within the SPAR method, choice of lead, ECG sampling frequency and machine learning model choice. We determined that using a K nearest neighbours (KNN) model with 125 Hz ECG sampling frequency, using specific features that quantified the density of the attractor, gave a classification accuracy of 81.2%. When using a decision tree model it was found that the sensitivity was 72.5% which shows an obvious improvement over 30-day long term monitoring which has a sensitivity of 34%. The results of this paper present consideration for the application of a new method to the clinically relevant problem of aiding detection of PAF and conjectures as to the reasoning behind these results. Further investigation in larger cohorts is needed to fully elucidate these findings.

Data availability

The datasets analysed for this study can be found on the Physionet website (https:/physionet.org/content/ptb-xl/1.0.3) .

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Acknowledgements

We thank Dr Jane Lyle for her help in developing the machine learning code at the beginning of the project.

Funding

This work was supported by a grant from the National Institute of Health Research Applied Research Collaboration Kent Surrey and Sussex.

Author information

Authors and Affiliations

  1. Department of Comparative Biomedical Sciences, School of Veterinary Medicine, University of Surrey, Daphne Jackson Road, Guildford, GU2 7AL, UK

    Steven Creasy & Kamalan Jeevaratnam

  2. School of Mathematics and Physics, University of Surrey, Guildford, UK

    Steven Creasy & Philip J. Aston

  3. Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK

    Gregory Y. H. Lip

  4. Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

    Gregory Y. H. Lip

  5. Cardiovascular Analytics Group, PowerHealth Limited, Kwai Chung, Hong Kong, China

    Gary Tse

  6. Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China

    Gary Tse

  7. School of Nursing and Health Studies, Hong Kong Metropolitan University, Kowloon, Hong Kong, China

    Gary Tse

  8. School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, UK

    Manasi Nandi

Authors
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  2. Gregory Y. H. Lip
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  3. Gary Tse
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  4. Manasi Nandi
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Contributions

All authors attest they meet the current ICMJE criteria for authorship.

Corresponding author

Correspondence to Kamalan Jeevaratnam.

Ethics declarations

Competing interests

Philip Aston and Manasi Nandi have a patent, WO2015121679A1, “Delay coordinate analysis of periodic data,” which covers the foundations of the Symmetric Projection Attractor Reconstruction (SPAR) method used in this paper. Steven Creasy, Gregory Lip, Gary Tse, and Kamalan Jeevaratnam have no competing interests to declare.

Ethics statement

The research in this paper was completed while adhering to the regulations of the University of Surrey review boards on human studies and animal care.

Patient consent statement

The data used in this paper was open source and was approved for publication by the Institutional Ethics Committee as anonymous data (PTB-2020-1).

Contribution to the field

Atrial fibrillation impacts a significant proportion of the adult population and is a serious risk factor for strokes. Detection is often difficult due to the brief nature of the episodes and as such long term monitoring has become the accepted method for diagnosis of atrial fibrillation. Studies have shown that long term monitoring is a fairly ineffective way to diagnose atrial fibrillation and so there is scope to improve the methodologies used. In this study we looked to apply a signal processing technique to electrocardiograms in conjunction with machine learning techniques to detect atrial fibrillation episodes after they had occurred. By investigating the impact of the sampling frequency of the electrocardiograms and optimising other parameters within the method we were able to not only detect atrial fibrillation after it had occurred but do so with a higher accuracy than current long term monitoring methods. This poses potential for a future change to the detection of atrial fibrillation for improved detection rate and also lower risk to the patients.

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Creasy, S., Lip, G.Y.H., Tse, G. et al. Classification of paroxysmal atrial fibrillation using sinus rhythm electrocardiograms using the symmetric projection attractor reconstruction method. Sci Rep (2026). https://doi.org/10.1038/s41598-026-37491-1

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  • Received: 22 August 2025

  • Accepted: 22 January 2026

  • Published: 18 February 2026

  • DOI: https://doi.org/10.1038/s41598-026-37491-1

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Keywords

  • Paroxysmal atrial fibrillation
  • Machine learning
  • Prediction
  • Electrocardiogram
  • SPAR analysis
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