Retraction of: Scientific Reports https://doi.org/10.1038/srep08209, published online 03 February 2015
The Editors have retracted this Article.
After publication, concerns have been raised about the integrity of some of the figures. Specifically,
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a blot for p-ERK1/2 in Figure 5 appears to be horizontally flipped and partially overlapping with the blot for ERK1/2 in Figure 11B in a different paper by the same authors1;
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a blot for p-SAPK/JNK in Figure 5 appears to be vertically flipped and partially overlapping with the blot for p-JNK in Figure 11C in1;
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FACS image for A779 in Figure 1 appears to be similar to Annexin V-FTC image in Figure 5 in a different paper by different authors2, control images between those figures also appear to overlap;
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FACS image for LPS in Figure 1 appears to be similar to ARAEC + image in Figure 6C in a different paper by different authors3;
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FACS image for LPS in Figure 1 appears to be also similar to miR-150 mimics image in Figure 6C in another different paper by different authors4;
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FACS image for ACE2 + A779 + LPS in Figure 1 appears to be similar to RAEC image in Figure 6 in3;
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FACS image for shACE2 + LPS in Figure 1 appears to be similar to the other ARAEC + image in Figure 6C in3;
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FACS image for ACE2 + LPS in Figure 1 appears to be similar to HL-60-LC + OA in Figure 4 in a different paper by different authors5.
The Editors requested provision of the original data underlying the paper, but received no reply from the Authors. The Editors therefore no longer have confidence in the integrity of the data in this Article.
Yingchuan Li, Yongmei Cao, Zhen Zeng, Mengfan Liang, Ying Xue, Caihua Xi, and Wei Jiang did not respond to the correspondence from the Editors about this retraction. The Editors were not able to confirm the current contact details for Ming Zhou.
References
Li, Y. et al. Angiotensin-converting enzyme inhibition attenuates lipopolysaccharide-induced lung injury by regulating the balance between angiotensin-converting enzyme and angiotensin-converting enzyme 2 and inhibiting mitogen-activated protein kinase activation. Shock 43, 395–404. https://doi.org/10.1097/SHK.0000000000000302 (2015).
Wang, C. et al. Knockdown of UbcH10 enhances the chemosensitivity of dual drug resistant breast cancer cells to epirubicin and docetaxel. Int. J. Mol. Sci. 16(3), 4698–4712. https://doi.org/10.3390/ijms16034698 (2015).
Liu, B. & Li, Y. G. Impact of conditional miRNA126 overexpression on apoptosis-resistant endothelial cell production. PLoS ONE 10(5), e0126661. https://doi.org/10.1371/journal.pone.0126661 (2015).
Feng, J. et al. miR-150 functions as a tumour suppressor in human colorectal cancer by targeting c-Myb. J. Cell. Mol. Med. 18(10), 2125–2134. https://doi.org/10.1111/jcmm.12398 (2014).
Ma, W. Caveolin-1 plays a key role in the oleanolic acid-induced apoptosis of HL-60 cells. Oncol. Rep. 32, 293–301. https://doi.org/10.3892/or.2014.3177 (2014).
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Li, Y., Cao, Y., Zeng, Z. et al. Retraction Note: Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis prevents lipopolysaccharide–induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF–κB pathways. Sci Rep 16, 7393 (2026). https://doi.org/10.1038/s41598-026-40543-1
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DOI: https://doi.org/10.1038/s41598-026-40543-1
